"The invisible D in my name is my mother's second most lasting contribution to my life."

'Wayne Le--known as "Invisible-D 'Wayne" at school--has been invited to participate in a seemingly ordinary, innocuous adolescent health study by a prestigious university. The study has a few nice perks, but most important to 'Wayne, is the opportunity to give his immigrant father an accomplishment to be proud of--something that's been in short supply since 'Wayne's mother left.

But the study quickly proves to be anything but ordinary and innocuous, and 'Wayne, his best friend Kermit, and a fellow study participant named Jane (a girl who shall not be manic-pixied) find themselves sucked into an M. C. Escheresque maze of conspiracies that might be entirely in their heads or might truly be a sinister government plot.