This new (August 2017) and expanded edition of The Dark Side of Statins completes the series.
All four of his statin books are equally informative, but he considered this to be both the best and the most important of his works.
The final chapter is a first-hand account of Dr Graveline's last weeks and days and the official causes of his death.
The full range of statin side effects includes cognitive dysfunction, behavioral and emotional disorders, chronic nerve and muscle damage and an ALS-like neuromuscular degenerative process, as major categories of damage.
Thousands of statin users, like myself, have been afflicted with peripheral neuropathies with a tendency to be resistant to all traditional medical treatment.
Statins inhibit not only dolichols, corrupting our DNA damage correction, but CoQ10 as well, increasing our damage load. Predictably the inevitable effect is increased mitochondrial DNA damage -- considered by many authorities to be the mechanism of our aging process as well as that of many chronic diseases.
Many of the statin side effects are permanent and weakness and fatigue are common complaints. Many statin victims say that abruptly, almost in the blink of an eye, they have become old people.
Statins block the synthesis of CoQ10 and dolichols, thereby contributing directly to the premature common chronic ills of aging. Since this involves normal physiologic processes, it is silent. By the time we become aware of it, it is already far too late and the damage has been done to those susceptible. This, in my judgment, is the truly Dark Side of Statins.
Duane Graveline, MD, MPH