One fateful day, all of humanity turned to stone. Many millennia later, Taiju frees himself from the petrification and finds himself surrounded by statues. The situation looks grim--until he runs into his science-loving friend Senku! Together they plan to restart civilization with the power of science!

The race across South America is on as the team dives into the Amazon rain forest, hoping to reach the source of petrification. When they arrive, Senku and friends discover a scene that's so full of malice it's sickening! Deeper into the Amazon--at the so-called Stone Sanctuary--the final battle against Stanley draws near!