A string of overdoses in Colorado Springs has Detectives Joe Kenda and Lee Wilson on the lookout for a bad batch of heroin that has been cut with a drug they've never seen before.
Meanwhile, at Springs General Hospital, Dr. Blair Moreland--the notoriously unpleasant head anesthesiologist--has found a way to feed his deepening addiction to the very same powerful new drug: fentanyl.
But when Dr. Moreland starts supplying the dangerous painkiller to dealer Lula Lopez--planning to manufacture the drug himself--he angers a Mexican crime syndicate and sets into motion a cycle of death and violence that threatens to engulf the entire city.
Detectives Kenda and Wilson must track down the source of this killer heroin before anyone else can overdose--and stop Moreland before he can escape the long arm of the law.