From the bestselling author of Charlie and the Chocolate Factory and Matilda comes the story of a not-so-lovely grandma, a boy, and a magical medicine.

George is alone in the house with Grandma. The most horrid, grizzly old grunion of a grandma ever. She needs something stronger than her usual medicine to cure her chronic grouchiness. A special grandma medicine, a remedy for everything. And George knows just what to put into it. Grandma's in for the surprise of her life-and so is George, when he sees the results of his mixture!