Daniel Bishop and Andre Gibson are best friends leading a life of crime in Las Vegas. After nearly a decade of robbing, gambling and hustling their way through the bowels of Sin City, they plan one final job to get out of the game for good: rob hotel and casino magnate Richard Reynolds. What they discover in pursuit of this big score is far more sinister than anticipated, placing them in the crosshairs of an ancient demon that feeds on human flesh and suffering.

After they first encounter the shapeshifting demon known as the Wendigo, Daniel and Andre travel to the Native American reservation north of town and meet Soaring Eagle, an elder in the Paiute tribe whose supernatural visions portend a dark future. His tribe's knowledge of the Wendigo proves crucial, as does the perspective of Soaring Eagle's daughter, Jennifer, the tribe's medical doctor.

What follows is an introspective journey for all involved; a reflection on class, criminality and corruption that leaves behind a trail of blood and shell casings.