Upon receiving a desperate letter from a relative, Bram Stoker, along with two childhood friends Jack and Andy set off from London to Transylvania to help. Once there, they uncover Vlad, an evil vampire, and try to stop him from harming others.

After returning to London, they discover Vlad has taken up residence in Whitechapel. Vlad soon begins to torment Bram with a series of headline making murders. During this time Bram, Jack and Andy uncover Vlad's possible motive for being in Whitechapel. With this knowledge Bram and his friends try to find Vlad and thwart his plans in an attempt to save humanity. But as most things with Vlad go, this is no easy task because he always appears to be two steps ahead.