In the aftermath of The Polar Shield Project, Jon Kent and Damian "Ian" Wayne are on the run! With their hometown in ruins and in the absence of their heroic fathers, Jon and Ian are on a mission to find a sample of the deadly virus that's threatening Wyndemere and Jon's mother, Lois Lane. Meanwhile, Candace follows clues that hold the key to her destiny as she unlocks powerful abilities she never knew existed. While their quests threaten to divide the three of them, it's only through teamwork and trust that they can succeed.