Jimmy Kudo, the son of a world-renowned mystery writer, is a high school detective who has cracked the most baffling of cases. One day while on a date with his childhood friend Rachel Moore, Jimmy observes a pair of men in black involved in some shady business. The men capture Jimmy and give him a poisonous substance to rub out their witness. But instead of killing him, it turns him into a little kid! Jimmy takes on the pseudonym Conan Edogawa and continues to solve all the difficult cases that come his way. All the while, he's looking for the men in black and the mysterious organization they're with in order to find a cure for his miniature malady.

A killer stalks a rich man's family, leaving a white glove at the scene of each crime. His latest victim leaves a dying message--claiming the killer is from Hades itself! Is Conan dealing with the devil?

Then Conan meets Satan...Satan Onizuka, that is, a washed-up rock star in demonic makeup. But is his devilish persona just an act for the fans? When Satan's agent is murdered, Conan starts to wonder what evil thoughts lurk beneath the mascara...