It is 1665 and the women of Eyam village keep many secrets. Especially Isabel and Mae.

Isabel Frith, the village midwife, walks a dangerous line with her herbs and remedies. There are men in the village who speak of witchcraft, and Isabel has a past to hide. So she tells nobody her fears about the pious, reclusive apothecary, on whom she is keeping a watchful eye.

Mae, the apothecary's youngest daughter, dreads her father's rage if he discovers what she keeps from him: her feelings for Rafe, Isabel's ward, or the fact that she studies from her father's books at night.

But others have secrets too. Secrets darker than any of them could have imagined.

When Mae makes a horrifying discovery, Isabel is the only person she can turn to. But helping Mae will place them both in unimaginable peril. Meanwhile another danger is on its way from London. One that threatens to engulf them all. . .