Dr. Sam Peebles was born in Nashville, Arkansas and reared in the rural community of Saratoga, Arkansas. He graduated from Harding College in Searcy, Arkansas. He graduated from the University of Arkansas School of Medicine in 1974. Dr. Peebles has been practicing medicine in Nashville, Arkansas since 1975. He was in Family Practice for the first eighteen years then became a full-time emergency physician. He has been married to his wife Suzanne since 1970. They had three children Amy, now deceased, Damon, and Samuel Jr. They have four grandchildren. They are members of the Blue Bayou Church of Christ which is located about five miles outside of Nashville. Dr. Peebles teaches a Bible class and leads singing.