Twenty-year-old Sibel thought she had concrete plans for the summer. She would care for her grandmother in Istanbul, visit her father's grave, and study for the MCAT. Instead, she finds herself watching Turkish soap operas and self-diagnosing her own possible chronic illness with the four humors theory of ancient medicine.

Also on Sibel's mind: her blond American boyfriend who accompanies her to Turkey; her energetic but distraught younger sister; and her devoted grandmother, who, Sibel comes to learn, carries a harrowing secret.

Delving into her family's history, the narrative weaves through periods of political unrest in Turkey, from military coups to the Gezi Park protests. Told with pathos and humor, Sibel's search for strange and unusual cures is disrupted as she begins to see how she might heal herself through the care of others, including her own family and its long-fractured relationships.