Zach is going about his normal day-playing with his dog, learning at school, and having fun with his friends. This is until he unknowingly encounters a gang of germs along the way that are on a mission to get him sick.

Travel on an exciting adventure with the devious germs-Gram, Pox, Cap, Cory, and Aden-as they attach to Zach, one by one, and teach him a lesson he won't soon forget.