Eli, a precocious 16-year-old social misfit living on Long Island in August 1979, cons his way into a professional boys' choir's Italian and Vatican tour so he can discover his missing father's legacy.
But when he meets his dream girl, Jane, and finds himself connected to an intricate murder plot involving a legendary drug, he must decide if singing for the Pope is worth losing his family and first love.
Jane, a rebellious 16-year-old American girl, is desperate to get back into favor with her school friends after accidentally calling a narc on them. When she is sent to a Roman convent for smuggling erotic novels, she realizes she must grow up fast if she's going to escape from the nuns, solve her family's mystery involving a mythical drug, keep clear of the authorities, and declare her love for Eli.