Steeped in rich historical detail, Dr. Eliza Edwards, the ingénue student in The Unlocked Path, becomes the mature mentor, steadfast in her calling to effect social change by addressing women's health issues and guiding others to realize their dreams. In 1936, as the Depression ravages careers, Eliza re-defines her abilities, traveling to Georgia and Tennessee as she reclaims her purpose and rediscovers her ambitions. Returning to Boston, she endures heartbreak with the eruption of World War II, bringing chaos to the world and sending her sons into battle. Will her unyielding pursuit to limit suffering and save lives sustain her amid the tumultuous landscapes of 1930s and 1940s America?