Middlemarch is set in the fictitious Midlands town of Middlemarch during 1829-32, and it comprises several distinct and intersecting stories and a large cast of characters. The narrative is variably considered to consist of three or four plots of unequal emphasis: the life of Dorothea Brooke; the career of Tertius Lydgate; the courtship of Mary Garth by Fred Vincy; and the disgrace of Bulstrode. Significant themes include the status of women, the nature of marriage, idealism, self-interest, religion, hypocrisy, political reform, and education.

Although containing comical elements, Middlemarch is a work of realism that refers to many historical events: the 1832 Reform Act, the beginnings of the railways, the death of King George iv, and the succession of his brother, King William iv. In addition, the work incorporates contemporary medical science and examines the deeply reactionary mindset found within a settled community facing the prospect of unwelcome change.

This case laminate collector's edition includes a Victorian inspired dust-jacket.