In 2010, Alex DiFrancesco had a different name and was a missing person. Alone in a mental hospital, they began to have fantasies of running away permanently, changing their name, growing a beard. In their journey to coming out as transgender, DiFrancesco moved from New York City to the Midwest. Psychopomps follows them on the search for family, marriage, relationships with other trans people, attempts to build community, and for the elusive link to ancient beliefs about the special spiritual role of the trans individual in society.