In the challenging context of accelerating climate dynamics, the core discipline of architectural design is evolving and embracing new forms of action. New York-based nonprofit Terreform ONE has established a distinctive design tactic that investigates projects through the regenerative use of natural materials, science, and the emergent field of socio-ecological design. This kind of design approach uses actual living matter (not abstracted imitations of nature) to create new functional elements and spaces. These future-based actions are not only grounded in social justice, but are also far-reaching in their application of digital manufacturing and maker culture. Terreform ONE tackles urgent environmental and urban social concerns through the integrated use of living materials and organisms.