Special's a working girl trying to scratch out a living on 42nd Street, the sleaziest strip in America. No pimp, no problem-she can handle herself. But when her friend gets butchered and an eyewitness dishes the details, Special begs her city official clients to track down the killer. That's when they try to kill her.

Now Special's on the run from the ugly truth: the cops are making the city "safe" by exterminating the prostitutes, pimps, thugs, gangsters, dealers, muggers, and junkies. And the only way she can survive is by teaming up with a drunk Santa to unleash anarchy. Down on the Deuce, anything can happen. But survival is never easy. And this time it's gonna take a miracle.